Given the significant prevalence of spinal cord injury in developed and developing societies and the involvement of all age groups, finding a new way to treat it is of interest to everyone. According to the World Health Organization, 250,000 to 500,000 people suffer from this problem every year, and this problem reduces their quality of life and increases their mortality. At present, the role of cell therapy and the use of stem cell types as reconstructive medicine in the treatment of damaged tissues is like spinal cord a new phenomenon. Nowadays, Zebrafish has been discussed to be used as a new and possibly the most effective approach in the treatment of spinal cord injuries. One of the reasons that makes this model superior to other conventional models is the ability of Zebrafish in repairs related to nerve injuries. The ability of axons to regrow rapidly after injury, the absence of permanent scarring, and no existence of immune rejection after transplantation are cases that strongly support this opinion. Zebrafish cells are in small size, growth rapidly and their genomes are very similar to the human genome that makes them suitable for research in this area. Also, the advanced cognitive behaviours of this animal are amazing. There is no need to use drugs that reduce the immune system in Zebrafish model due to absence of immune rejection unlike other animal models. Therefore, these advanced features and significant superiorities in Zebrafish model should be further researched so that it can be used to discover the secrets of repairing spinal cord injuries.
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