Title: Combined use of deep brain stimulation and spinal neurostimulation in a patient with Parkinson's disease and operated spine syndrome (clinical case)

Abstract

Spine degenerative lesions, particularly spinal stenosis and segmental instability, are often associated with Parkinson's disease (PD). A contributing factor to the cascade of degenerative changes in spinal structures is the disruption of the sagittal balance of the spine-pelvis axis. Among all comorbid conditions in PD, pain syndromes of various etiologies and varying degrees of severity occur in 92.3%. Back pain is the most common and occurring in 59.4%. Camptocormia (CC) among outpatients with PD ranges from 3 to 17%. Surgical treatment of PD patients, including CC for spinal deformities, has recently become much more common. However, despite performing fixation surgeries on the spine, the impairment of the statics and dynamics of the spine is progressing and accompanied by further increase in pain syndrome. Information about the use of DBS in the treatment of PD-associated CC is accumulating in the current literature. However, there is no consensus among researchers on the choice of the optimal structure for deep brain stimulation (DBS) for the treatment of CС.The information about the combined use of different stimulation systems in one patient in available literature wasn't found.

Biography

Naryshkin Alexander Gennadievich graduated from the medical faculty of the Leningrad Sanitary and Hygienic Medical Institute in 1979. From 1984 to 1990 he worked as a neurosurgeon in the clinic of the USSR Academy of Medical Sciences. From 1990 to 1993 he was a neurosurgeon at the clinic of the “Human Brain Institute”. From 1993 to 2005 he was the head of the neurosurgical departments of city hospitals. Since January 2006 he has been working at the "V. M. Bekhterev National Medical Research Center for Psychiatry and Neurology” as the leading scientific associate of the neurosurgical department. In 1991 he defended his dissertation "Clinical and pharmacological approaches to pathogenetic treatment of phantom pain syndrome". In 2006 he became a doctor of medical sciences with dissertation "The clinical and methodological aspects of transtimpanal chemical destruction of vestibular receptors as a new method of functional neurosurgery (with the example of cervical dystonia)”. He is a professor in the A.L. Polenov Neurosurgery Department of the Federal State Budgetary Institution of Higher Professional Education. The author of more than 200 publications, 10 inventions, and 16 textbooks.