The damage of the protective covering (myelin sheath) that surrounds nerve fibers in brain, optic nerves and spinal cord leads to development of demyelinating disorders. The damaged myelin sheath makes the nerve impulses slow or even stop, causing neurological problems. Demyelination causes neurological deficits, such as vision changes, weakness, altered sensation, and behavioral or cognitive problems. Demyelination can occur at any age.
Symptoms of demyelinating diseases include
Genetic mutations, infectious agents, autoimmune reactions, Vitamin B12 deficiency and other unknown factors results in dysmyelination.
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