Stem Cells and Neuroregeneration

The term neuroregeneration refers to the regrowth or repair of nervous tissues, cells or cell products. Research in this field in going on to understand the basic mechanisms involved in neurodegeneration or neurologic injury. However, due to the complex structures of the nervous system, the regeneration process becomes extremely challenging. The brain, spinal cord and peripheral nerves which are susceptible to various types of injury ranging from trauma to neurodegenerative diseases that cause progressive deterioration is unfortunately often irreversible, and a very little spontaneous regeneration, repair or healing occurs.

Stem cell therapies hold promising future in terms of neurological treatment. Neural stem cells (NSCs)  has the potential to replace lost tissue after nervous system injury. Hence, stem cells can promote host neural repair in part by secreting growth factors. Stem cells holds a great promise for treating many neurological disorders, researches showed that it can reduce the total damage to peripheral nerves and improving tissue regeneration. Neurological disorders such as Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis (ALS), Alzheimer's disease, multiple sclerosis (MS), stroke, and spinal cord injury are caused by a loss of neurons and glial cells in the brain or spinal cord.

Researchers have successfully generated neurons and glial cells from stem cells.Investigators have done extensive research to develop and carry out stem cell-based brain transplantation therapies.Stem cell research is in progress for the development of novel therapies to cure a wide range of neurological disorders.